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Current supplementation protocol calls for repeated parenteral injections of hydroxycobalamin over 6 weeks bypassing the diseased tissue

doi: 10.1371/journal.pone.0139491

Potential ROS induction pathways include the NF-B, mitogen-activated protein kinase, phosphoinositide 3-kinaseAkt, and Keap1Nrf2ARE signaling pathways 39

Those taking the Release supplement had a greater reduction in waist circumference than the placebo group